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Ernährung und Allergie

Internet Symposium on Food Allergens 1(3): 121-134 (1999) http://www.food-allergens.de


Allergen Data Collection:
Codfish (Gadus morhua)
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Abstract

IgE-mediated hypersensitivity to fish is a common problem in fish processing communities. Fish allergy is more frequent in children and young adults of whom about 88 % show IgE-mediated reactions to codfish.  The codfish inhabits the North, Baltic and White Sea, and the Northern Atlantic and Pacific. It is used as a fresh, salted, dried or more recently as a processed food ingredient of e.g. surimi. Although food processing such as cooking and canning could alter the allergenic potency of codfish allergens, one should be aware of the retained significant allergenicity of these products. An overview of prevalence data, symptoms, diagnostic and therapeutic features of codfish allergy as well as molecular biological and allergenic properties of codfish allergens is given in tabular form. The major allergen from codfish Gad c 1 (Allergen M) belongs to the Ca2+-binding parvalbumins. Despite the high degree of cross-reactivity to other fish species some species may be tolerated by certain allergic individuals.
 
 
Contents
1 Prevalence of Codfish Allergy
2 Symptoms of Codfish Allergy
3 Diagnostic Features and Therapy of Codfish Allergy
4 Composition of Codfish
5 Allergens of Codfish
5.1 Sensitization to Codfish Allergens
5.2 Allergen M  (Gad c 1)
5.3 41-kDa-Allergen
6 Isolation & Preparation
7 Cross-Reactivities
8 Stability of Codfish Allergens
9 Allergen Sources
10 References


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