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Ernährung und Allergie

Internet Symposium on Food Allergens 1(4):161-75 (1999) http://www.food-allergens.de


Allergen Data Collection:
Hazelnut (Corylus avellana)
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Abstract

Type 1 allergy to hazelnut is highly associated to pollen allergens from trees of the order Fagales (birch, alder, hazel, hornbeam, and oak). Prevalence of hazelnut hypersensitivity in tree pollen allergic patients ranges from about 70 to 90%. Allergic reactions to tree nuts are often severe, including anaphylactic reactions occurring after accidental ingestion. Hazelnut is responsible for about 13% of acute allergic reactions in tree nut sensitive patients. Frequency of hazelnut allergy is higher in adults than in children. Predictive values of skin tests and specific IgE are relatively low. Detailed information on prevalence, symptoms, and diagnostic features of hazelnut allergy as well as cross-reactivities, molecular biological and allergenic properties of the major hazelnut and hazel pollen allergens are reviewed in tabular form. The major hazel pollen allergen (Cor a 1) as well as the major hazelnut 18-kDa allergen are cross- reactive to Bet v 1 from birch pollen. A 14-kDa hazelnut allergen cross- reacts with birch profilin (Bet v 2). Moreover, several heat stable hazelnut allergens have been identified which are independent of birch pollen. Hazelnut is a common ingredient in processed foods, mainly in confectionery products. Hazelnut oils which are not fully refined may potentially be a threat for nut allergic individuals.
 
 
Contents
1 Prevalence of Hazelnut Allergy
2 Symptoms of Hazelnut Allergy
3 Diagnostic Features of Hazelnut Allergy
4 Composition of Hazelnut
5 Allergens of Hazelnut
5.1 Sensitization to Hazelnut Allergens
5.2 18-kDa Allergen
5.2 Major Pollen Allergen (Cor a 1)
6 Isolation & Preparation
7 Cross-Reactivities
8 Stability of Hazelnut Allergens
9 Allergen Sources
10 Allergenicity of Hazelnut Varieties
11 References


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